One-pot catalytic enantioselective domino nitro-michael/michael synthesis of cyclopentanes with four stereocenters

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Abstract

A highly enantioselective organocatalytic one-pot synthesis of nitro-, formyl-, and ester-functionalized cyclopentanes with four stereocenters is presented. The cyclopentanes were formed as a predominant diasteroisomer and isolated in high yields with 97-99% ee. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

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Zhao, G. L., Ibrahem, I., Dziedzic, P., Sun, J., Bonneau, C., & Córdova, A. (2008). One-pot catalytic enantioselective domino nitro-michael/michael synthesis of cyclopentanes with four stereocenters. Chemistry - A European Journal, 14(32), 10007–10011. https://doi.org/10.1002/chem.200801082

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