Region Specific Vulnerability to Lipid Peroxidation in the Human Central Nervous System

Abstract

Around 100 billion neurons in the human nervous system orchestrate an exceptionally wide range of motor, sensory, regulatory, behavioural, and executive functions. Such diverse functional output is the product of different molecular events occurring in nervous cells and particularly, neurons. Morphologically, central nervous system (CNS) neurons differ in size, number and complexity of dendrites, number of synaptic connections, length of axons and distance across which synaptic connections are established, extent of axonal myelination …