Models to Study Colonisation and Colonisation Resistance

Abstract

This review describes various in vivo animal models (humans; conventional animals administered antimicrobial agents and animals species used; gnotobiotic and germ-free animals), in vitro models (luminal and mucosal), and in silico and mathematical models which have been developed to study colonisation and colonisation resistance and effects of gut ?ora on hosts. Where applicable, the advantages and disadvantages of each model are discussed.