Abstract
Silencing of BMAL1 and PER1 stimulates melanogenic activity of follicular and epidermal melanocytes, indicating a novel role for peripheral circadian clock processes in the regulation of melanin pigmentation. Linking the expression levels of BMAL1PER1 with changes in melanogenesis opens exciting opportunities to study the role of the local molecular clock in modulation of melanocyte functions in the hair follicle and the epidermis with attendant effects on epidermal barrier functions in general.
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CITATION STYLE
Slominski, A. T., Hardeland, R., & Reiter, R. J. (2015, April 20). When the Circadian Clock Meets the Melanin Pigmentary System. Journal of Investigative Dermatology. Nature Publishing Group. https://doi.org/10.1038/jid.2014.553
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