Carcinogenicity and mutagenicity of malathion and its two analogues: A systematic review

0Citations
Citations of this article
16Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Malathion has been widely used world-wide in arbovirus control programs. In 2015, it was classified by the International Agency for Research on Cancer (IARC) as a probable carcin-ogen to humans. This work aimed to systematize the evidence of the carcinogenic and mutagenic effects associated with the exposure of malathion and its analogs, malaoxon and isomalathion. The search was carried out in Toxline, PubMed and Scopus databases for original papers published from 1983 to 2015. In all, 73 papers were selected from a total of 273 eligible papers. The results of in vitro and in vivo studies showed mainly genetic and chromosomal damages caused by malathion. The epidemiological studies evidenced significant positive associations for thyroid, breast, and ovar-ian cancers in menopausal women. This evidence of the carcinogenic effect of malathion should be considered before its use in arbovirus control programs.

Cite

CITATION STYLE

APA

Bastos, P. L., Bastos, A. F. T. de L., Gurgel, A. D. M., & Gurgel, I. G. D. (2020, August 1). Carcinogenicity and mutagenicity of malathion and its two analogues: A systematic review. Ciencia e Saude Coletiva. Associacao Brasileira de Pos - Graduacao em Saude Coletiva. https://doi.org/10.1590/1413-81232020258.10672018

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free