Determination of the absolute configuration of yessotoxin, a polyether compound implicated in diarrhetic shellfish poisoning, by NMR spectroscopic method using a chiral anisotropic reagent, methoxy-(2-naphthyl)acetic acid

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Abstract

The absolute configuration of yessotoxin (1), a potent diarrhetic toxin causative of shellfish poisoning, was determined by NMR-spectroscopy using a chiral anisotropic reagent, methoxy-(2-naphthyl)acetic acid (2NMA), which was applied to a monoacetate of bisdesulfated yessotoxin (3).

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Takahashi, H., Kusumi, T., Kan, Y., Satake, M., & Yasumoto, T. (1996). Determination of the absolute configuration of yessotoxin, a polyether compound implicated in diarrhetic shellfish poisoning, by NMR spectroscopic method using a chiral anisotropic reagent, methoxy-(2-naphthyl)acetic acid. Tetrahedron Letters, 37(39), 7087–7090. https://doi.org/10.1016/0040-4039(96)01580-8

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