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Dietary coenzyme Q10 suppressed hepatic hydroxymethylglutaryl-CoA reductase activity in laying hens

Bioscience, Biotechnology and Biochemistry (2013) 77(7) 1572-1574
DOI: 10.1271/bbb.130039
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Abstract

The effects of dietary coenzyme Q10 (CoQ10) on cholesterol metabolism in laying hens were investigated. Dietary CoQ10 significantly reduced egg yolk cholesterol content and suppressed hepatic hydroxymethylglutaryl-CoA reductase (HMGR) activity. It is therefore likely that CoQ10 acts as an HMGR inhibitor in the livers of laying hens, which in turn results in a reduction in egg-yolk cholesterol.

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Honda, K., Saneyasu, T., Motoki, T., Park, Y., & Kamisoyama, H. (2013). Dietary coenzyme Q10 suppressed hepatic hydroxymethylglutaryl-CoA reductase activity in laying hens. Bioscience, Biotechnology and Biochemistry, 77(7), 1572–1574. https://doi.org/10.1271/bbb.130039

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