Human non-CG methylation

  • Dyachenko O
  • Schevchuk T
  • Kretzner L
  • et al.
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Abstract

Non-CG methylation is well characterized in plants where it appears to play a role in gene silencing and genomic imprinting. Although strong evidence for the presence of non-CG methylation in mammals has been available for some time, both its origin and function remain elusive. In this review we discuss available evidence on non-CG methylation in mammals in light of evidence suggesting that the human stem cell methylome contains significant levels of methylation outside the CG site. © 2010 Landes Bioscience.

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Dyachenko, O. V., Schevchuk, T. V., Kretzner, L., Buryanov, Y. I., & Smith, S. S. (2010). Human non-CG methylation. Epigenetics, 5(7), 569–572. https://doi.org/10.4161/epi.5.7.12702

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