Marjolin's ulcer: A case report and literature review

Abstract

There is currently no agreed standard for the definition, classification, etiology, pathological type, location, treatment and prognosis of Marjolin's ulcer (MU). The present study report a case of a 50-year-old male with inguinal lymph node and bone metastases from an MU on a burn scar on the left lower extremity. The patient carried this scar since he was 1 year old and had a chronic scar ulcer ever since. A histopathological examination of the inguinal lymph nodes and the ulcer demonstrated well-differentiated squamous cell carcinoma. Extensive resection was performed; however, the tumor eventually led to bone metastasis in the tibia. A more thorough second surgical resection that included the regional lymph nodes was more effective as the tumor did not recur. The present case report is complemented by presenting a review of the relevant literature, with an aim of aiding in the development of a preliminary clinical path for MU.