Harnessing the stem cell potential in the human hippocampus to limit cognitive aging

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Abstract

The field of human adult neurogenesis has been controversial despite mounting evidence. The authors propose moving beyond debating the existence of adult neurogenesis and towards discovering strategies to harness endogenous stem cell potential for resilience against cognitive aging.

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Mhatre, S., & Moore, D. L. (2026). Harnessing the stem cell potential in the human hippocampus to limit cognitive aging. PLoS Biology, 24(5), e3003787. https://doi.org/10.1371/journal.pbio.3003787

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