Species Difference and Tissue Distribution of Uridine Diphosphate-Glucuronyltransferase Activities toward E6080,1-Naphthol and 4-Hydroxybiphenyl

Abstract

The apparent in vitro kinetic constants of uridine diphosphate-glucuronyltranferase (UDP-GT) activities towards E6080, 1-naphthol (1-N) and 4-hydroxybiphenyl (4-HB) were determined using microsomes, to assess the effect of inducing agents and evaluate species and tissue differences. © 1992, The Pharmaceutical Society of Japan. All rights reserved.