Immune modulation: Turncoat regulatory T cells

Abstract

The article focuses on regulatory T cells which have the power to suppress the immune response to fight disease such as cancer and autoimmune diseases. It states that people and mice are affected with severe autoimmune diseases because of less in a transcription factor called forkhead box protein-3 (FoxP3). An overview of a study conducted by Zhou et al on the precautions to use to T cells in the clinic is offered.