Electrodiffusion model simulation of ionic channels: 1D simulations

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Abstract

The drift-diffusion (Poisson-Nernst-Planck) model is applied to ionic channels in biological membranes plus surrounding solution baths. Simulations of the K channel in KCl solutions using the TRBDF2 method are presented which show significant boundary layers at the ends of the channel. The computed current-voltage curve for the K channel shows excellent agreement with experimental measurements. © Kluwer Academic Publishers 2004.

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Gardner, C. L., Nonner, W., & Eisenberg, R. S. (2004). Electrodiffusion model simulation of ionic channels: 1D simulations. Journal of Computational Electronics, 3(1), 25–31. https://doi.org/10.1023/B:JCEL.0000029453.09980.fb

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