Microbiological applications of high-resolution melting analysis

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Abstract

High-resolution melting (HRM) analysis uses real-time PCR instrumentation to interrogate DNA sequence variation and is a low-cost, single-step, closed-tube method. Here we describe HRM technology and provide examples of varied clinical microbiological applications to highlight the strengths and limitations of HRM analysis. Copyright © 2012, American Society for Microbiology. All Rights Reserved.

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Tong, S. Y. C., & Giffard, P. M. (2012, November). Microbiological applications of high-resolution melting analysis. Journal of Clinical Microbiology. https://doi.org/10.1128/JCM.01709-12

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