Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth with Perinatal Human Immunodeficiency Virus in the DC Cohort

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Abstract

We conducted a retrospective analysis of 38 children and youth with human immunodeficiency virus (aged 0-19 years) in the United States and report an increased rate of change of BMI-for-age z score after initiating integrase strand transfer inhibitors (+0.19 z score units/year [95% confidence interval,. 01-.37]; P=.036) for a median follow-up of 527.5 days.

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Koay, W. L. A., Dirajlal-Fargo, S., Levy, M. E., Kulie, P., Monroe, A., Castel, A. D., … Abbott, S. (2021). Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth with Perinatal Human Immunodeficiency Virus in the DC Cohort. Open Forum Infectious Diseases, 8(7). https://doi.org/10.1093/ofid/ofab308

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