Chemical constituents of Coutaportla ghiesbregthiana: Co-crystallization of two ent-nor-kaurene diterpenes

Abstract

The known nor-diterpene (16R)-ent-17-hydroxy-19-nor-kaur-4-en-3-one and the new norditerpene (16R)-ent-19-nor-kaur-4-en-3-oxo-17-oic acid were obtained as a crystalline mixture from roots of C. ghiesbregthiana. Their structures were deduced by spectroscopic means and confirmed by a X-ray diffraction study of the crystalline mixture. Additionally, ursolic and betulinic acids, skimmin, and sucrose were isolated. This is the first chemical study of a member of the Coutaportla genus. © 2005 Verlag der Zeitschrift für Naturforschung.