HDlive flow for diagnosis of invasive mole

Abstract

Our experience of using HDlive flow or HDlive flow silhouette to diagnose invasive moles is presented. In the first case, a large ill-defined hypervascular mass occupying the entirety of fundal and anterior lesions of the uterus was identified using HDlive flow silhouette. The patient was successfully treated with methotrexate. In the second case, a circumscribed hypervascular tumor of the uterus was identified with HDlive flow. This patient was refractory to methotrexate and actinomycin-D and was successfully treated with etoposide, methotrexate, actinomycin D, cyclophosphamide, vincristine (EMA/CO). Based on ultrasound features, the difference in drug susceptibility between chemosensitive and refractory invasive moles may be due to the vascularity of the mass in the uterus.