Estimation of Current and Future Physiological States in Insular Cortex

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Abstract

Livneh et al. find that slow changes in ongoing population activity patterns in insular cortex reflect physiological need states independent of behavior and hypothalamic hunger/thirst neurons. Food/water cues and consumption drive population activity to transiently “simulate” a future satiety state.

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Livneh, Y., Sugden, A. U., Madara, J. C., Essner, R. A., Flores, V. I., Sugden, L. A., … Andermann, M. L. (2020). Estimation of Current and Future Physiological States in Insular Cortex. Neuron, 105(6), 1094-1111.e10. https://doi.org/10.1016/j.neuron.2019.12.027

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