Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia

  • Kenter G
  • Welters M
  • Valentijn A
  • et al.
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Abstract

Vulvar intraepithelial neoplasia is a chronic disorder caused by high-risk types of human papillomavirus (HPV), most commonly HPV type 16 (HPV-16). Spontaneous regression occurs in less than 1.5% of patients, and the rate of recurrence after treatment is high.

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Kenter, G. G., Welters, M. J. P., Valentijn, A. R. P. M., Lowik, M. J. G., Berends-van der Meer, D. M. A., Vloon, A. P. G., … Melief, C. J. M. (2009). Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia. New England Journal of Medicine, 361(19), 1838–1847. https://doi.org/10.1056/nejmoa0810097

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