Trastorno esquizoafectivo: ¿Cuánto de esquizofrenia? ¿Cuánto de bipolar?

Abstract

Introduction: Schizoaffective Disorder represents a controversial clinical entity, in regard to nosology and classification criteria. It has been considered as a variant of Schizophrenia, as a mixed entity between Schizophrenia and Bipolar Disorder and as a Bipolar Disorder subtype Method: Classificatory, clinical issues, neuropsychology and genetics research contributions are reviewed. Discussion and Conclusion: Schizoaffective Disorder concept at present time, differs from its original description, maintaining lack of definitive clarity with respect to its nosology. Considering neurocognitive impairment within its course, Schizoaffective Disorder looks much closer to affective psychosis than to Schizophrenia. From genetic research field emerges data that challenge the classic dichotomist distinction between affective psychosis and Schizophrenia established by E. Kraepelin, raising again the question about thinking in psychosis as a continuum in which Schizoaffective Disorder could represent an intermediate state.