Effect of Isosorbide on Hearing Loss due to Endolymphatic Hydrops

Abstract

Hearing change was studied in 130 ears (94 patients) with endolymphatic hydrops before and after an 8-week administration of isosorbide. Hearing was markedly improved in 50 (38.5%) of the ears. This hearing improvement showed a significant positive correlation with the glycerol test results. Therefore, the response to isosorbide therapy of hearing loss with the endolymphatic hydrops can be predicted by the results of the glycerol test. © 1993, The Society of Practical Otolaryngology. All rights reserved.