Capillary Electrophoresis Coupled To Mass Spectrometry for Forensic Analysis

Abstract

In this review the most important techniques, which are developed to hyphenate capillary electrophoresis to mass spectrometry (CE-MS), suitable for forensic analysis, are summarized. Analytes of interest are divided into four main parts, namely, compounds with amine containing side chains, compounds with N-containing saturated ring structures, other heterocycles and peptides. Sample pre-treatments and direct injection modes used in CE-MS for forensic analysis are briefly discussed from critical point of view. Special emphasis is placed to point out the advantages of mass spectrometric detection compared to UV- and laser- induced fluorescence (LIF) detections.