Prevalence of priapism in individuals with sickle cell disease and implications on male sexual function

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Abstract

OBJECTIVE: To evaluate epidemiological aspects of priapism in patients with sickle cell disease, and these aspects impact on adult sexual function. METHODS: This was a cross-sectional study including individuals with sickle cell disease who were evaluated at a reference center for sickle cell. Participants completed a structured questionnaire about their sociodemographic characteristics and priapism events. Sexual function was assessed using validated two instruments, the Erection Hardness Score and one about the sex life satisfaction. RESULTS: Sixty-four individuals with median aged of 12 (7 to 28) years were interviewed. The prevalence of priapism was 35.9% (23/64). The earliest priapism episode occurred at 2 years of age and the latest at 42 years. The statistical projection was that 71.1% of individuals of the study would have at least one episode of priapism throughout life. Patients with episodes of priapism (10/23) had significantly worse erectile function Erection Hardness Score of 2 [1-3]; p=0.01 and were less satisfied with sexual life 3 [3-5]; p=0.02. CONCLUSION: Priapism is usually present in childhood, and severe episodes are associated with cavernous damage, impairment in the quality of the erection, and lower sexual satisfaction.

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Alvaia, M. A., Maia, H. A. A. da S., Nelli, A. de M., Guimarães, C. O. S., Carvalho, E. S. de S., Netto, J. M. B., … Bessa Júnior, J. de. (2020). Prevalence of priapism in individuals with sickle cell disease and implications on male sexual function. Einstein (Sao Paulo, Brazil), 18, eAO5070. https://doi.org/10.31744/einstein_journal/2020AO5070

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