THIAZOLIDINEDIONE DERIVATIVES AS ANTIDIABETIC AGENTS: A SHORT REVIEW

Abstract

In the present scenario, researchers focused themselves on thiazolidine ring-based compound to cure Diabetes Mellitus. Diabetes mellitus is a heterogeneous group of disease, characterized by a state of chronic hyperglycemia, resulting from diversity of etiologies, environmental and genetic, acting jointly. The thiazolidinediones used in oral combination therapy in management of patients with type II diabetes who have insufficient glycemic control despite maximal tolerated dose of oral mono-therapy with either metformin or sulphonyl urea.