Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment

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Abstract

An adenoviral transduction-based mouse model that can be infected with SARS-CoV-2 provides a tool to understand host factors involved in viral infection and clearance as well as potential therapeutic modalities.

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Sun, J., Zhuang, Z., Zheng, J., Li, K., Wong, R. L. Y., Liu, D., … Zhao, J. (2020). Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment. Cell, 182(3), 734-743.e5. https://doi.org/10.1016/j.cell.2020.06.010

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