Ty elements of the yeast saccharomyces cerevisiae

Abstract

Transposable elements in the yeast Saccharomyces cerevisiae are a heterogeneous group of mobile genetic elements. Ty elements transpose via an intermediate RNA-molecule using the same replication and integration mechanisms as the metazoan retroviruses. Ty1 is a retrotransposons with life cycle very similar to that of oncogenes. This similarity provides an attractive model for virus-host interaction in a genetically tractable eukaryote. Like oncogenes, responds to carcinogens with an increased formation of Ty1 mRNA. There are many articles, concerning the structure, transposition cycle and regulation, as well as post-transcriptional regulation of transposition by Saccharomyces cerevisiae Ty retrotransposons. In this review, we will observe recent advances in our understanding of structure, transposition and regulation of Ty retrotransposition in Saccharomyces cerevisiae. © 2005 Taylor and Francis Group, LLC.