Signet ring cell carcinoma

Abstract

Signet ring cell carcinoma is very rare carcinoma of colon and aggressive subtype of colorectal carcinoma that is mostly diagnose inadvance stage. 5-year survival rate is very poor as compared to other adenocarcinoma of the colon. First case reported in 1951 but clinical literature on this subtype of adenocarcinoma is very limited. In this report a 32-year old male presented with SRCC of colon. Our literature review describes the many factors that contribute to the poor outcome and high recurrence in SRCC of the colon. This study prove that survival rate is increased by earlydiagnosis and surgical resection. However, the rarity of this cancer and its propensity for insidious onset and aggressive course prove a challenge to the development of such guidelines.