Cell motility as random motion: A review

Abstract

The historical co-evolution of biological motility models with models of Brownian motion is outlined.Recent results for how to derive cell-type-specific motility models from experimental cell trajectories are reviewed.Experimental work in progress, which tests the generality of this phenomenological model building is reported.So is theoretical work in progress, which explains the characteristic time scales and correlationsof phenomenological models in terms of the dynamics of cytoskeleton, lamellipodia, and pseudopodia. © EDP Sciences/Societè Italiana di Fisica/Springer-Verlag 2008.