Timing of colonoscopy and outcomes in patients with lower GI bleeding: A nationwide population-based study

Abstract

Background The role of urgent colonoscopy in lower GI bleeding (LGIB) remains controversial. Population-based studies on LGIB outcomes are lacking. Objective To investigate the impact of the timing of colonoscopy on outcomes of patients with LGIB. Design Cross-sectional study. Setting Nationwide Inpatient Sample 2010. Patients International Classification of Diseases, Ninth Revision, Clinical Modification codes identified patients with LGIB who underwent colonoscopy. Main Outcome Measurements In-hospital mortality, length of stay, and hospitalization costs in patients who underwent early (≤24 hours) or delayed (>24 hours) colonoscopy. Results A total of 58,296 discharges with LGIB were identified; 22,720 had a colonoscopy performed during the hospitalization. A total of 9156 patients had colonoscopy performed within 24 hours (early colonoscopy), and 13,564 had colonoscopy performed after 24 hours (delayed colonoscopy). There was no difference in mortality in patients with LGIB who had early versus delayed colonoscopy (0.3% vs 0.4%, P =.24). However, patients who underwent early colonoscopy had a shorter length of hospital stay (2.9 vs 4.6 days, P