Efficient synthesis of the pentasaccharide repeating unit of the o -Antigenic polysaccharide of escherichia coli o166 strain

Abstract

An efficient strategy has been developed for the synthesis of the pentasaccharide repeating unit of the cell-wall polysaccharide of Escherichia coli O166 strain through sequential stereoselective glycosylations of monosaccharide intermediates. All the glycosylation steps were high-yielding with high stereoselectivities.