Preanesthetic sedation of preschool children using intranasal midazolam

Abstract

This present study demonstrates that intranasal midazolam produces anxiolysis and sedation in preschool children with a rapid onset similar to that previously described for the same drug using the rectal route, and for a different drug (sufentanil) using the intranasal route. No additional benefit was seen from the higher dosage; thus, we recommend using the lower dose of 0.2 mg/kg midazolam.