Photoinduced strategies towards strained molecules

Abstract

New photoinduced strategies towards radical reactions of strained molecules such as [1.1.1]propellane and bicyclo[1.1.0]butanes by photoredox or metallaphotoredox catalysis have recently been disclosed. Such strategies enable the controllable construction of 1,3-difunctionalized bicyclo[1.1.1]pentanes, cyclobutanes, and drug-like analogues, and offer new opportunities for reaction design of [1.1.1]propellane and other strained molecules.