Monoclonal antibodies against the fusion protein are protective in necrotizing mumps meningoencephalitis

  • Löve A
  • Rydbeck R
  • Utter G
  • et al.
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Abstract

A monoclonal antibody against the fusion (F) protein of mumps virus was found to confer marked protection in mumps virus-induced encephalitis. Almost total prevention of extensive brain necrosis was found. This study indicates that the virus F protein is directly involved in the pathogenesis of brain necrosis.

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Löve, A., Rydbeck, R., Utter, G., Orvell, C., Kristensson, K., & Norrby, E. (1986). Monoclonal antibodies against the fusion protein are protective in necrotizing mumps meningoencephalitis. Journal of Virology, 58(1), 220–222. https://doi.org/10.1128/jvi.58.1.220-222.1986

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