A T-cell receptor γ/CD3 complex found on cloned functional lymphocytes

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Abstract

Cloned blood lymphocytes that do not express the α- and β-chains of the T-cell receptor show MHC-unrestricted cytotoxicity. These cells carry the γ-protein, disulphide-linked either to another molecule or to itself, and associated with the CD3 complex. These observations may help to solve the mystery posed by the discovery of the γ gene. © 1987 Nature Publishing Group.

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Borst, J., Van De Griend, R. J., Van Oostveen, J. W., Ang, S. L., Melief, C. J., Seidman, J. G., & Bolhuis, R. L. H. (1987). A T-cell receptor γ/CD3 complex found on cloned functional lymphocytes. Nature, 325(6106), 683–688. https://doi.org/10.1038/325683a0

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