Efficacy and Safety of Nasal Administration of “Na-no-L-DOPA” Based on PLGA Nanoparticles

I.G. Kondrasheva; T.A. Antipova; G.G. Barsegyan; P.Ye. Gambaryan; A.A. Guseva; A.A. Kamensky

Journal ArticleOPEN ACCESS

Efficacy and Safety of Nasal Administration of “Na-no-L-DOPA” Based on PLGA Nanoparticles

Kondrasheva I
Antipova T
Barsegyan G
et al.

Engineering (2012) 04(10) 27-29

DOI: 10.4236/eng.2012.410b007

N/ACitations

17Readers

Abstract

Inclusion of L-DOPA, the standard Parkinson's disease medication, into polymeric particles (PLGA) results in optimization the drug metabolism and increasing its bioavailability, significantly increases of physical endurance, better coordination and lower anxiety in Wistar rats, when chronically administered nasally.

Cite

CITATION STYLE

APA

Kondrasheva, I. G., Antipova, T. A., Barsegyan, G. G., Gambaryan, P. Ye., Guseva, A. A., & Kamensky, A. A. (2012). Efficacy and Safety of Nasal Administration of “Na-no-L-DOPA” Based on PLGA Nanoparticles. Engineering, 04(10), 27–29. https://doi.org/10.4236/eng.2012.410b007

Efficacy and Safety of Nasal Administration of “Na-no-L-DOPA” Based on PLGA Nanoparticles

Abstract

Cite

Register to see more suggestions