Serum Biochemistry Profiles in Confirmed Effusive Feline Infectious Peritonitis Cats

Abstract

Feline infectious peritonitis (FIP) is one of the most challenging diseases due to difficulties in treatment. A reliable and fast diagnosis is crucial to the best prognosis. The aim of this study was to evaluate the serum biochemistry profile of cats with confirmed effusive FIP. A total of 32 cats suspected of showing clinical symptoms at Animal Clinic, Faculty Veterinary Medicine, Universitas Gadjah Mada were used in this study. Ten serum biochemistry from cats who had been diagnosed with effusive FIP were analyzed. The diagnosis was based on clinical examination, ultrasound, rivalta test, and PCR. The serum chemistry profiles showed the average levels of SGPT and SGOT in effusive FIP were increased 132.2±36.3 IU/L and 103.3±48.7 IU/L respectively (P<0.05). The average albumin has normal range of 2.3±0.1 g/dL. Hyperglobulinemia was found in 90% of samples with an average of 6.8±0.4 g/dL (P<0.05). All cats have low albumin-globulin ratio with an average of 0.3±0.2 (P<0.05). The serum biochemistry profiles in effusive FIP cats including increased levels of SGPT and SGOT, hypoalbuminemia, hyperglobulinemia, and the decreased ratio albumin-globulin.