Suppression of Clostridium difficile by normal hamster cecal flora and prevention of antibiotic-associated cecitis

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Abstract

Administration of normal cecal homogenates decreased numbers of viable Clostridium difficile and prevented cecitis in antibiotic-challenged hamsters. Cecal anaerobes appeared to suppress C. difficile.

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Wilson, K. H., Silva, J., & Fekety, F. R. (1981). Suppression of Clostridium difficile by normal hamster cecal flora and prevention of antibiotic-associated cecitis. Infection and Immunity, 34(2), 626–628. https://doi.org/10.1128/iai.34.2.626-628.1981

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