Analysis of Drug Effectiveness and Efficiency of Use of Amlodipine-Captopril Combination Compared to Amlodipine-Valsartan in the X Hospital Patients of Bogor

Abstract

Prevalence of people with hypertension are increased with the increasingly cost of health, especially the cost of drug and hypertension including disease with long life medication therefore, we need cost effectiveness analysis for hypertension in order to assist in making effectiveness the drug selection decisions by benefit and cost. This study aim to find out difference of cost-effectiveness between amlodipine-captopril combination and amlodipine-valsartan on hypertension inpatient with BPJS in X Hospital of Bogor. Cost effectiveness analysis was conducted troughpayers perspective namely BPJS from direct medical cost. The output is patient blood pleasure after medication with antihipertensi. Cost effectiveness analysis using value of ACER based difference on ratio between cost with output. Based on sociodemography hypertension inpatient most widely male sex (57,8%), age 56-65 years old (33,3%), housewife profession (36,7%), and last education in elementary school (33,3%). Result revealed theres difference of effectivity therapy and theres difference of cost effectiveness between amlodipine-captopril combination and amlodipine-valsartan combination, based on ACER value of amlodipine-captopril combination was Rp.19.361,9 and it is smaller than value ACER of amlodipine-valsartan combination was Rp 27.655,8.Indicating that amlodipine-captopril combination more effective and more cost-effective than amlodipine-valsartan.