Abstract
10-Deacetoxytaxol (9) and 10-deoxytaxotere (10) have been prepared from 10-deacetylbaccatin III by attachment of the C-13 side-chain and deoxygenation. 10-Deacetoxytaxol is comparable to taxol in its cytotoxicity to P-388 cells, but 10-deoxytaxotere is significantly more cytotoxic than taxol. © 1993.
Cite
CITATION STYLE
APA
Chaudhary, A. G., & Kingston, D. G. I. (1993). Synthesis of 10-deacetoxytaxol and 10-deoxytaxotere. Tetrahedron Letters, 34(31), 4921–4924. https://doi.org/10.1016/S0040-4039(00)74046-9
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