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Non-coding regions of the Ebola virus genome contain indispensable phylogenetic and evolutionary information

Science China Life Sciences (2015) 58(7) 682-686
DOI: 10.1007/s11427-015-4857-9
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Abstract

We compared the numbers of nucleotide substitutions occurring in the non-coding regions and coding regions of Ebola virus genomes and found that non-coding regions contain indispensable phylogenetic and evolutionary information. The omission of genetic data from non-coding regions can lead to unreliable phylogenies and inaccurate estimates of evolutionary parameters.

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Jiang, X. Q., Zhang, Z. J., Zhuang, D. M., Carr, M. J., Zhang, R. L., Lv, Q., & Shi, W. F. (2015). Non-coding regions of the Ebola virus genome contain indispensable phylogenetic and evolutionary information. Science China Life Sciences, 58(7), 682–686. https://doi.org/10.1007/s11427-015-4857-9

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