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Gene selection in microarray survival studies under possibly non-proportional hazards

Bioinformatics (2010) 26(6) 784-790
DOI: 10.1093/bioinformatics/btq035
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Abstract

Motivation: Univariate Cox regression (COX) is often used to select genes possibly linked to survival. With non-proportional hazards (NPH), COX could lead to under- or over-estimation of effects. The effect size measure c=P(T1

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Dunkler, D., Schemper, M., & Heinze, G. (2010). Gene selection in microarray survival studies under possibly non-proportional hazards. Bioinformatics, 26(6), 784–790. https://doi.org/10.1093/bioinformatics/btq035

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