Photocontrolled chignolin-derived β-hairpin peptidomimetics

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Abstract

The synthesis of novel, chignolin-derived peptides comprising the azobenzene photoswitch [3-(3-aminomethyl)phenylazo]phenylacetic acid (AMPP) is reported. Reversible photoswitching behavior led to folding into β-hairpin-like structures, as unequivocally demonstrated by CD, FT-IR and NMR spectroscopy. This journal is

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Podewin, T., Rampp, M. S., Turkanovic, I., Karaghiosoff, K. L., Zinth, W., & Hoffmann-Röder, A. (2015). Photocontrolled chignolin-derived β-hairpin peptidomimetics. Chemical Communications, 51(19), 4001–4004. https://doi.org/10.1039/c4cc10304a

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