Trends in incidentie, prognose en sterfte bij spierinvasief blaascarcinoom

Abstract

There is a slightly decreasing trend in the risk for Dutch men to be diagnosed with a muscle-invasive bladder cancer (MIBC) and the risk of dying from MIBC. For women, the reverse is true. These trends are mainly caused by changes in smoking behavior in the past decades. Strikingly, the five-year survival of MIBC has not changed during the past decades. There is some improvement, however, in the postoperative mortality. Patients under the age of 75 years with a cT2–cT4aN0M0 tumor are being treated mainly with cystectomyand increasingly with neo-adjuvant chemotherapy. Such patients over the age of 75 years are mainly treated with radiotherapy or no treatment with curative intent at all.