Construction of spirocarbocycles: Via gold-catalyzed intramolecular dearomatization of naphthols

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Abstract

A highly efficient, gold-catalyzed intramolecular dearomatization reaction of naphthols via 5-endo-dig cyclization is described. This facile and direct approach furnishes spirocarbocycles in excellent yields under mild conditions.

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Wu, W. T., Xu, R. Q., Zhang, L., & You, S. L. (2016). Construction of spirocarbocycles: Via gold-catalyzed intramolecular dearomatization of naphthols. Chemical Science, 7(5), 3427–3431. https://doi.org/10.1039/c5sc04130a

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