Conversion of epoxides to bromohydrins by B-bromobis (dimethylamino) borane

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Abstract

Reaction of the title reagent with 1-alkene oxides regioselectively yields the corresponding 1-bromo-2-alkanols, while the more substituted bromide predominates in the cases of styrene oxide and 1-methylcyclohexene oxide. © 1986.

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Bell, T. W., & Ciaccio, J. A. (1986). Conversion of epoxides to bromohydrins by B-bromobis (dimethylamino) borane. Tetrahedron Letters, 27(7), 827–830. https://doi.org/10.1016/S0040-4039(00)84111-8

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