The Effect of Cajanus Cajan Seeds Extraction on Some Haematological Parameters Among Haemorrhagical Anaemic Rats in Khartoum–Sudan

Abstract

Background: Worldwide different plants were studied for their role in the treatment and correction of different types of anaemia’s. The Medicinal and Aromatic Plants Research Institute (MAPRI) of the National Centre for Research (NCR) plays major role in medicinal and aromatic plants investigation, determination of therapeutic properties and documented in Sudan. Objectives: This study used to determine the effect of Cajanus Cajan seeds extract on the some haematological parameters among hemorrhagic anaemia rats, Khartoum –Sudan. Methods: Experimental randomised controlled trial study conducted among 24 healthy Wistar albino rats with both sex, ages (6weeks) and weighing between (75- 130g), they were feed with standard laboratory chow. they divided into four groups each one consists of six rats. Result: Dose group(800 mg/kg/day) represent highly significant increases in haemoglobin in W0&W1 P value < 0.001,and W0&W3 p value is 0.0002.while the dose of 400mg/kg/day significant increase in W0&W1 p value is< 0.003 and W0&W3 p<0.00004, in the dose of 200mg/kg/day represent also significant increase at W0&W1 p<0.005 and in W0&W3p<0.007 respectively, when compared to control values(Group1). Conclusion: This study revealed that there are increased in some haematological parameters and lend support to the use of ethanol seeds extract of Cajanus Cajan in treatment of hemorrhagic anaemia.