Histology of the rat vas deferens after infection of a non-occlusive chemical contraceptive

Abstract

An alternate co-polymer of styrene and maleic anhydride was dissolved in dimethylsulphoxide and injected into the vas deferens of rats. The polymer was retained in the vas deferens and the morphological changes detected were confined to the mucosa. When the polymer was removed by flushing dimethylsulphoxide, the mucosal structure became normal within 2 weeks.