Development of novel expression systems for actinomycetes

Abstract

Streptomycetes1) are Gram-positive soil microorganisms that produce a wide variety of secondary metabolites, many of which have potent biological activities. They are used to produce more than half of the known biologically active microbial products including many commercially important antibiotics, immunosuppressive compounds, animal health products, and agrochemicals2). They are used to obtain various enzymes that are commercially and academically valuable3). This vast reservoir of diverse products makes the