Activity of extract seed moringa oleifera on gene expression of (Efb1) gene in candida dubliniensis isolated from oral candidiasis to cancer patients

Abstract

Gene expression of EFB1 gene in yeast Candida dubliniensis isolated from oral candidiasis in cancer patients was detected using by R-time PCR for some isolates before and during the yeast infection of the epithelial cells. The results showed a high rate of gene expression of T2 (42.104 ± 6.533) and a significant difference at the probability level P>0.01 compared with the treatment was c (1.034 ± 0.126) and the use of the Moringa oleifera extract was 25% to evaluate its effect on the gene expression (ALS1) before and during yeast infection of epithelial cells. The results showed that the gene expression of T1 was decreased by (0.129 ± 0.021) compared to (C) value (1.034 ± 0.126). As for the T2 treatment was gene expression at a rate (42.104 ± 6.533) high Compared with T3 treatment in which gene expression dropped at a rate (22.143 ± 4.176) and with a significant difference at the level of the probability of P ≤ 0.01.