Synthesis and Characterization of New Silicone Hydrogels Contact lenses Based on TRIS-DMA-AA-NVP Via Photo Polymerization for Biomedical Application

Abstract

The purpose of the present work is to designate the synthesis of innovative soft silicone hydrogel contact lenses founded on Acrylic acid (AA) ,N,N dimethylacrylic amide (DMA),and 1-vinyl 2- pyrolidone(NVP) was polymerized via free fundamental polymerization in the existence of 1,6 hexandioldiacrylate (HDODA) as a crosslinker and 1-hydroxycyclohexyl phenyl ketone as photoinitiator. The polymerized materials were characterized fully for its use fullness as an intraocular lens by various techniques. FTIR was implemented to discover  the whole conversion of3-(methacryloyloxy) propyl TRIS (trimethylsiloxy) silane monomer into silicone hydrogels contact lens. The silicon hydrogels contact lenses were manufactured from silicon and different hydrophilic monomers, copolymerization of  3-(methacryloyloxy) propyl( TRIS) (trimethylsiloxy) silane with acrylic acid ,N,N-dimethylacrylamide, and N-Vinylpyrrolidone(NVP) with different ratio (70,80,90)%.To explore three sequences of silicone hydrogel ingredients for their classification, water component, transmittance, mechanical feature , oxygen penetrability) Dk), protein adsorption and  bacterial connection as potential contact lens materials as well as tackles  the connections between water kinship and optical, mechanical, oxygen permeable with biological features.The outcomes displayed that the water affinity might be moderated through the hydrophilic monomers. The Equilibrium Water Component (EWC) rose with increasing hydrophilic monomer value. Generally, the outcomes revealed that visible light transmittance inclines to increase as well as tensile mechanical features obtained  in decreasing trend relying  on the growing EWC. The Dk worth declined firstly then was rose once the EWC was from 25 to 75%. The sum of Staphylococcus aurous close to the silicone hydrogels surface of the was fell by61 to 140.This work may provide information on preparing functional silicone hydrogels for contact lenses application.